P.Mean: Meta-analysis for a single mean estimate (created 2010-02-11).

Someone noted that the usual meta analysis is carried out for the study on two treatment groups, usually for a difference in means. What if you had several studies estimating not a difference in means, but just estimates of a single mean. Could you conduct a meta-analysis in this situation?

Yes, you can  do this. The statistics change slightly, but in a predictable and logical way. The general concept and the general procedures stay the same.

It gets a bit trickier when the statistic of interest is a single proportion (e.g., sensitivity/specificity), especially when there are some publications where the proportion equals 1.0. If you try to weight by the inverse variance, these studies get infinite weight.

Creative Commons License This work is licensed under a Creative Commons Attribution 3.0 United States License. This page was written by Steve Simon and was last modified on 2010-04-01. Need more information? I have a page with general help resources. You can also browse for pages similar to this one at Category: Systematic overviews.