Large randomized controlled trials are ready for retirement

*Recommendation
2014
Randomization
Author

Steve Simon

Published

January 17, 2014

Dean Ornish contributes his response to a series of invited essays on the topic “What Scientific Idea is Ready for Retirement?” His choice is the large randomized controlled trial. While I believe his criticism is too one-sided, he does raise some interesting points about the difficulty in using large trials to assess behavioral interventions.

Ornish D. Edge: What Scientific Idea Is Ready for Retirement–Large Randomized Controlled Trials. Available in html format.

While we’re at it, take a look at

Earlier versions are here and here.